Arcadia (itch) Mac OS

'Arcadia is neither good nor evil, but merely a place for good and evil' Welcome to Arcadia! A Realm of Magic and Mystery. You play as Aureas Pias, a war hero who, upon returning from the war on the western continent, is tasked by the gods with righting the wrongs commited during his time at war, so that a cursed mask can be taken off his head.

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Physician Assistant

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  • Patients experiencing cardiac arrest are treated according to ACLS protocols, however current protocols lack recommendations for the treatment of refractory Ventricular Fibrillation which persists after more than 3 cycles of CPR and defibrillation. One potential intervention for these cases that is being researched is the use of simultaneous or sequential activation of two defibrillators.

Title

Author

Date of Award

Spring 2021

Arcadia (itch) mac os 11

Degree Name

Master of Medical Science (Physician Assistant)

Department

Physician Assistant; College of Health Sciences

First Advisor

Elizabeth Masten, MS, PA-C, Principal Faculty, Clinical Coordinator

Abstract

Introduction: MDMA, or 3,4-methylenedioxymethamphetamine, is a psychoactive chemical which stimulates the release of serotonin, oxytocin, prolactin, and cortisol. Up until it became a Schedule I drug in 1985, making the chemical completely illegal in the US, MDMA was used as an “adjunct to the therapeutic process” in therapeutic settings, though no known controlled therapeutic studies were performed up until that point. More recently, research has been conducted studying the effects of MDMA-Assisted Psychotherapy on helping to eliminate the fear responses common in patients afflicted with PTSD. Some researchers have further hypothesized that MDMA has a stronger, longer lasting effect on reducing these symptoms of PTSD than the traditional therapies used today. This document will be using the current available research to analyze how the efficacy of MDMA-Assisted Psychotherapy compares to the efficacy of traditional psychotherapy in treating anxiety symptoms in 18-40 year old patients diagnosed with PTSD.

Methods: The articles discussed in this paper were obtained via EBSCO research databases, google scholar, and google. Inclusion criteria involve the articles must discuss the effects of MDMA-assisted psychotherapy on PTSD, the effects of MDMA-assisted psychotherapy on anxiety, the pharmacodynamics of MDMA and how it can be used in treatment for mental illness, how MDMA-assisted psychotherapy compares to traditional psychotherapy, or any combination of the above parameters. All articles used for the research needed to be scholarly and peer-reviewed.

Results: The final research studies analyzed included five randomized control trials and one meta-analysis of randomized controlled studies. Three of these studies showed a significant difference in the reduction of CAPS scores between MDMA-AP and placebo-assisted psychotherapy (P < 0.05) and one study showed that this difference was not clinically significant (P > 0.05). The two remaining studies did not measure outcomes using CAPS scores but did show significant differences in the reduction of SSPTSD scores (P < 0.05) and LSAS scores (P < 0.05) for the group using MDMA-assisted psychotherapy compared to the group using placebo-assisted psychotherapy. Of these studies, only two had a patient population of >25 and three had a population size between 25 and 10.

Conclusion: A number of studies supporting MDMA-Assisted psychotherapy show promise as an alternative breakthrough therapy for patients with refractory anxiety symptoms of PTSD. However, change in the DEA’s drug scheduling and an increase in larger longitudinal studies with more diverse sample populations would be necessary before current practices can be changed and the therapy can be recommended for clinical use.

Recommended Citation

Beasley, Blake, 'The Efficacy of MDMA-Assisted Psychotherapy Compared to the Efficacy of Traditional Psychotherapy in Treating Anxiety-Related Symptoms in 18–40-Year-Old Adults Diagnosed With Post-Traumatic Stress Disorder (PTSD)' (2021). Capstone Showcase. 81.
https://scholarworks.arcadia.edu/showcase/2021/pa/81

Additional Files

Blake Beasley Capstone 2021.mp4 (14375 kB)
PICO Final Paper Edited.docx (96 kB)

Included in

Alternative and Complementary Medicine Commons, Mental Disorders Commons

COinS

The Efficacy of MDMA-Assisted Psychotherapy Compared to the Efficacy of Traditional Psychotherapy in Treating Anxiety-Related Symptoms in 18–40-Year-Old Adults Diagnosed With Post-Traumatic Stress Disorder (PTSD)

Introduction: MDMA, or 3,4-methylenedioxymethamphetamine, is a psychoactive chemical which stimulates the release of serotonin, oxytocin, prolactin, and cortisol. Up until it became a Schedule I drug in 1985, making the chemical completely illegal in the US, MDMA was used as an “adjunct to the therapeutic process” in therapeutic settings, though no known controlled therapeutic studies were performed up until that point. More recently, research has been conducted studying the effects of MDMA-Assisted Psychotherapy on helping to eliminate the fear responses common in patients afflicted with PTSD. Some researchers have further hypothesized that MDMA has a stronger, longer lasting effect on reducing these symptoms of PTSD than the traditional therapies used today. This document will be using the current available research to analyze how the efficacy of MDMA-Assisted Psychotherapy compares to the efficacy of traditional psychotherapy in treating anxiety symptoms in 18-40 year old patients diagnosed with PTSD.

Methods: The articles discussed in this paper were obtained via EBSCO research databases, google scholar, and google. Inclusion criteria involve the articles must discuss the effects of MDMA-assisted psychotherapy on PTSD, the effects of MDMA-assisted psychotherapy on anxiety, the pharmacodynamics of MDMA and how it can be used in treatment for mental illness, how MDMA-assisted psychotherapy compares to traditional psychotherapy, or any combination of the above parameters. All articles used for the research needed to be scholarly and peer-reviewed.

Results: The final research studies analyzed included five randomized control trials and one meta-analysis of randomized controlled studies. Three of these studies showed a significant difference in the reduction of CAPS scores between MDMA-AP and placebo-assisted psychotherapy (P < 0.05) and one study showed that this difference was not clinically significant (P > 0.05). The two remaining studies did not measure outcomes using CAPS scores but did show significant differences in the reduction of SSPTSD scores (P < 0.05) and LSAS scores (P < 0.05) for the group using MDMA-assisted psychotherapy compared to the group using placebo-assisted psychotherapy. Of these studies, only two had a patient population of >25 and three had a population size between 25 and 10.

Conclusion: A number of studies supporting MDMA-Assisted psychotherapy show promise as an alternative breakthrough therapy for patients with refractory anxiety symptoms of PTSD. However, change in the DEA’s drug scheduling and an increase in larger longitudinal studies with more diverse sample populations would be necessary before current practices can be changed and the therapy can be recommended for clinical use.

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A downloadable game for Windows, macOS, and Linux

A woman alone in a house. A mystery and a love story. Explore the present to uncover the past, in a short story of love and loss and a life well-lived.

A narrative exploration that examines a world where memories are constantly fading and jumbled. A game about dementia and what happens when you can't hold onto the things you've done or the people you've loved.


Purchase link for Before I Forget is at the bottom of this page.

Dave Tucker's beautiful original soundtrack for Before I Forget is available here:



3-Fold Games is proud to partner with Alzheimer’s Research UK, to raise vital funds and awareness for dementia research, this World Alzheimer’s Month.

From 00:00 BST on 20 September to 00:00 BST on 4 October, 3-Fold games will be making a donation to Alzheimer’s Research UK for every product sold on Itch.

Before I Forget

For every game sold £0.61 + VAT will be paid* to Alzheimer’s Research UK**

The Garden radio play

For every game sold £0.15 + VAT will be paid* to Alzheimer’s Research UK**

Before I Forget and The Garden radio play bundle

For every game sold £0.72 + VAT will be paid* to Alzheimer’s Research UK**

Check out Alzheimer’s Research UK’s website for full details.

*Paid to Alzheimer’s Research Trading Limited which covenants all its taxable products to Alzheimer’s Research UK.

** Alzheimer’s Research UK is a registered charity with charity numbers 1077089 and SC042474.


“Is this the right place?...What did I come out here for?”

A plaintive theme on the piano. A tattered 2-year-old calendar. The taste of stale air. A woman is in her house, alone, and her mind holds a mystery...

You are Sunita - a woman living with early onset dementia. As you wander from room to room, you discover mysterious objects, each holding a fleeting, fragmented memory. Examine faded postcards, scribbled notes, photographs, and more to uncover Sunita’s past, piece together her life-story, and understand her present.

Before I Forget is a story-rich, first-person exploration game from 3-Fold Games. Delicate, moving, and atmospheric, it examines the emotional impact of dementia.

  • Short & Sweet: Before I Forget is a short narrative gem from 3-Fold Games. With an average playtime of 1 hour, it’s designed to be experienced in one sitting.
  • Story Rich: Sunita’s house is a treasure-trove of faded memories. The game-world of Before I Forget is expressive, detailed, and rich with backstory, taking you on a profound emotional journey.
  • Vocal Talent: Featuring a vivid cast of voice actors, breathing life into Sunita and her memories. (Including Anjali Kunapaneni & Bushra Laskar)
  • Original Soundtrack: Elegant piano melodies guide you through Sunita's internal and external worlds, with an all-original score from composer, Dave Tucker. Musical refrains that search and wind like an old memory


“We wanted to have some aspects that indicated Sunita’s Indian heritage apart from her name, and I actually did this piece of art in a little bit of software that came on my Galaxy phone, [...] so this is my homage, my paltry homage - to a really fantastic Indian - female Indian - painter [...] called Amrita Sher-Gil.”

Before I Forget comes with a free Developers’ Commentary, which you can activate from the game’s loading screen.

Arcadia (itch) Mac Os Download

As you explore Sunita’s house, listen to thought-provoking interviews with the game devs as they analyse their creative processes, reveal secrets, and much more.


REVIEWS:

‘A delicate and unique exploration of dementia from a first-person perspective’ Mark Serrels, Cnet

‘Beautiful and thought-provoking game’
Katie Campbell, Pos’ability Magazine


3-Fold Games are a small but mighty micro-studio from game developers Claire Morwood & Chella Ramanan. Dedicated to telling diverse stories from underrepresented perspectives, the creative duo make it their mission to create games which give voice to individuals/groups who are often excluded from game narratives.

Website:https://www.3foldgames.uk/

Follow us: @3foldgames

Follow the developers: @shimmerwitch @ChellaRamanan

Sign up to our newsletter: https://www.3foldgames.uk/

Press kit:


Minimum System Requirements
WINDOWS:
OS: Windows 7
Processor: 2.20GHz Processor
Memory: 2 GB RAM
Graphics: Intel HD4000 or equivalent
DirectX: Version 9.0c
Storage: 1 GB available space

MAC:
OS: OS X v10.11 El Capitan or higher
Processor: 2.20GHz Processor
Memory: 2 GB RAM
Graphics: Intel HD4000 or equivalent
Storage: 1 GB available space

LINUX:
Processor: 2.20GHz Processor
Memory: 2 GB RAM
Graphics: Intel HD4000 or equivalent
Storage: 1 GB available space

StatusReleased
PlatformsWindows, macOS, Linux
Release date Jul 16, 2020
Rating
Author3-Fold Games
GenreAdventure
TagsAtmospheric, Exploration, First-Person, Immersive, Narrative, Story Rich, Walking simulator
LinksSteam

Purchase

In order to download this game you must purchase it at or above the minimum price of $7.99 USD. You will get access to the following files:

Arcadia (itch) Mac Os 11

Development log

  • Before I Forget launch!
    Jul 16, 2020

Community

Arcadia (itch) Mac Os X

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